BioSamples database: the global hub for sample metadata and multi-omics integration

Area of Science:

• Bioinformatics
• Data Management
• Life Sciences

Background:

• The European Bioinformatics Institute's BioSamples database is a key resource for biological sample metadata.
• It supports the findable, accessible, interoperable, and reusable (FAIR) principles for diverse datasets.
• BioSamples integrates metadata from major EMBL-EBI archives like ENA, ArrayExpress, and EFG.

Purpose of the Study:

• To detail technical enhancements in the BioSamples database.
• To showcase improved user experience and increased sample registration capabilities.
• To illustrate the utility of BioSamples in connecting multi-omics data and creating data portals.

Main Methods:

• Technical updates focused on scalability and user interface improvements.
• Development of new features to support diverse data integration.
• Documentation of four use cases demonstrating community adoption and application.

Main Results:

• Successful implementation of technical updates leading to better performance.
• Enhanced sample registration and data discoverability.
• Demonstrated value through successful use cases in multi-omics data integration and portal creation.

Conclusions:

• BioSamples is a vital, evolving resource for biological sample metadata management.
• The database facilitates data sharing and reuse, adhering to FAIR principles.
• Ongoing development ensures BioSamples remains a central hub for life science data.