Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

9.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.8K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.9K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the implementation of Electronic Palliative Care Co-ordination Systems (EPaCCS) and optimising future service provision for palliative and end-of-life care: a synopsis of the Optimal Care mixed-method study.

Health and social care delivery research·2026
Same author

Characteristics, Diagnosis, and Treatment of Aphasia in Patients With Brain Tumors: A Scoping Review.

Neurology·2026
Same author

Development and usability testing of a mindfulness-based smoking cessation app for adults with low income: "It's helped me to not react and grab a cigarette".

Journal of health psychology·2026
Same author

Evaluation of Postblock Hypersensitivity Using Quantitative Sensory Testing before, during, and after Axillary Brachial Plexus Block Resolution in Healthy Volunteers.

Anesthesiology·2026
Same author

Feasibility and Acceptability of mPallCare<i>,</i> a Digital Health Intervention for People Living With Advanced Cancer in a Refugee Settlement in Uganda: Mixed Methods Study.

JMIR mHealth and uHealth·2026
Same author

<b>E</b>quitable <b>P</b>alliative care <b>I</b>n the <b>C</b>ommunity through <b>P</b>rimary <b>C</b>are (EPIC-PC) study protocol: a realist study to propose a new integrated neighbourhood team approach to palliative care.

BMJ open·2026

Related Experiment Video

Updated: Jan 11, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.7K

Pilot Testing of a Multicomponent Cancer Pain-Cognitive Behavioral Therapy mHealth App for Patients With Advanced

Desiree R Azizoddin1,2, Sara M DeForge1, Jian Zhao1

  • 1Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences, Oklahoma City, OK.

JCO Clinical Cancer Informatics
|November 13, 2025
PubMed
Summary

A mobile health intervention integrating pain-cognitive behavioral therapy (pain-CBT) with opioid management was feasible and acceptable for advanced cancer patients. While not statistically significant, qualitative data showed improved pain self-management knowledge and coping skills.

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.9K
Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

1.9K

Related Experiment Videos

Last Updated: Jan 11, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.7K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.9K
Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

1.9K

Area of Science:

  • Oncology
  • Digital Health
  • Pain Management

Background:

  • Advanced cancer patients frequently experience pain, necessitating effective management strategies.
  • Pain-cognitive behavioral therapy (pain-CBT) is effective but faces access limitations.
  • Mobile health (mHealth) offers a potential solution to improve access to pain management interventions.

Purpose of the Study:

  • To assess the feasibility and acceptability of an mHealth intervention for advanced cancer pain.
  • The intervention integrated pain-CBT with opioid education and tracking.
  • The goal was to improve chronic pain management in patients with advanced cancer.

Main Methods:

  • A 28-day smartphone-based intervention was tested in adults with advanced cancer and significant pain using opioids.
  • Feasibility was defined as ≥50% app usage, and acceptability was measured using the E-scale.
  • Intervention assessed pain, mood, catastrophizing, sleep, and opioid use, providing adaptive interventions and psychoeducation.
  • Pre-post surveys and qualitative interviews were conducted to evaluate outcomes and patient experiences.

Main Results:

  • 32 patients enrolled, with 59% meeting the ≥50% app-use feasibility threshold.
  • The intervention demonstrated good acceptability (mean E-scale score: 24.85).
  • No statistically significant reductions in pain intensity, interference, or catastrophizing were observed at 4- and 6-week follow-ups.
  • Qualitative interviews revealed increased pain self-management knowledge, enhanced coping skills, and reduced opioid stigma.

Conclusions:

  • The mHealth pain-CBT intervention is feasible and acceptable for patients with advanced cancer pain.
  • Exploratory analyses did not show significant improvements in pain outcomes.
  • Qualitative findings suggest meaningful patient engagement and skill development, warranting further efficacy testing.