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Published on: December 20, 2024
Patients with allergic rhinitis are more likely to need a secondary adenoidectomy after 6 months
Sofia Piperno1, Truman Archer2, Sawyer Archer2
1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Insights
Patients with allergic rhinitis are more likely to require a second adenoidectomy after the initial surgery. This study highlights the long-term impact of allergic rhinitis on adenoidectomy outcomes.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Allergy and Immunology
Background:
- Adenoidectomy is a common pediatric procedure, often necessitated by adenoid hypertrophy.
- Allergic rhinitis is a frequent comorbidity linked to adenoid hypertrophy.
- Progressive adenoid hypertrophy can lead to symptoms requiring surgical intervention.
Purpose of the Study:
- To evaluate the impact of allergic rhinitis on the need for secondary adenoidectomy over time.
- To compare secondary adenoidectomy rates in patients with and without allergic rhinitis post-primary adenoidectomy.
Main Methods:
- Utilized the TriNetX database for patient data and statistical analysis.
- Compared a cohort with allergic rhinitis to a control group without the condition, both having undergone primary adenoidectomy.
- Employed propensity score matching for cohort balancing and analyzed secondary adenoidectomy rates at various time points.
Main Results:
- Assessed 65,106 pediatric patients.
- No significant difference in secondary adenoidectomy rates was observed within the first 0.5 years post-primary surgery.
- A statistically significant increase in secondary adenoidectomy rates was found in patients with allergic rhinitis after 0.5 years.
Conclusions:
- Patients diagnosed with allergic rhinitis demonstrate a higher likelihood of requiring a secondary adenoidectomy.
- The increased need for repeat surgery becomes evident more than 0.5 years after the initial adenoidectomy.
- Allergic rhinitis is a significant factor influencing long-term outcomes following adenoidectomy.
Background:
Adenoidectomy, without concomitant procedures like tonsillectomy, is the third most common ambulatory pediatric operation. Allergic rhinitis is a common comorbidity that is known to cause adenoid hypertrophy. With time and progression, adenoid hypertrophy can become symptomatic and necessitate removal. Our aim is to assess how patients diagnosed with allergic rhinitis affect the need for a secondary adenoidectomy over time.
Methods:
We queried the TriNetX database and produced the statistical analysis for this project. The control group consisted of patients who have not been diagnosed with allergic rhinitis and have undergone a primary adenoidectomy. Cohorts were balanced using native TriNetX propensity matching before analysis. Outcomes measured included the presence of secondary adenoidectomy after 0-0.5, 0.5-1, 1-2, 2-3, 3-4, 4-5, 5-7, and 7+ years of primary adenoidectomy.
Results:
65,106 patients were assessed with a mean average age of 6.36 ± 7.82 and 6.34 ± 7.71 years between the control and experimental group. There was no difference in secondary adenoidectomy occurrences between the two groups between 1 day and 0.5 years after primary adenoidectomy (p = 0.896, RR 1.632 (0.922,2.888)). There was a difference between 0.5 and 1 year (p < 0.0001), 1-2 years (p < 0.0001), 2-3 years (p < 0.0001), 3-4 years (p = 0.001), 4-5 years (p = 0.001), 5-7 years (p = 0.0002), and more than 7 years (p = 0.0023).
Conclusions:
After 0.5 years of primary adenoidectomy surgery, patients diagnosed with allergic rhinitis are more likely to need a secondary adenoidectomy compared to their counterparts not diagnosed with allergic rhinitis.
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