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Updated: Jan 11, 2026

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management
Published on: September 2, 2015
Numerical study on thermo-mechanical interaction in skin tissue with temperature-dependent properties under
Yingze Wang1, Zhaowei He1, Sheng Zhang1
1School of Energy and Power Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Abstract:
The combined application of pulsed laser irradiation and cryogen spray cooling (CSC) is a promising technique for treating deep skin lesions, such as port wine stains (PWS). However, optimizing this process requires a precise understanding of the dynamic thermo-mechanical responses in skin tissue under sequential cold and heat stimuli. This study presents a comprehensive bio-thermo-mechanical coupling model incorporating temperature-dependent physical properties and the dual-phase lag (DPL) bioheat transfer mechanism. The finite difference method is employed to numerically solve the governing equations, enabling the prediction of temperature, displacement, thermal stress, and thermal damage distributions in multi-layered skin tissue. Comparative analyses reveal the significant influence of temperature-dependent properties and laser parameters on the thermo-mechanical response. The results demonstrate that CSC effectively reduces epidermal thermal damage while inducing notable compressive stress, highlighting the need for balanced clinical protocols.
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