Numerical study on thermo-mechanical interaction in skin tissue with temperature-dependent properties under

Yingze Wang1, Zhaowei He1, Sheng Zhang1

  • 1School of Energy and Power Engineering, Jiangsu University, Zhenjiang, 212013, PR China.

Journal of Thermal Biology
|November 13, 2025
PubMed
Summary

Cryogen spray cooling combined with pulsed laser irradiation treats deep skin lesions. This study models the thermo-mechanical response, finding cryogen spray cooling reduces epidermal damage but increases compressive stress, necessitating balanced treatment protocols.

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