Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

298
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
298
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

453
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
453
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

254
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
254
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

239
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
239
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

1.0K
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
1.0K
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

519
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
519

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-flow nasal cannula oxygen during breaks from noninvasive ventilation after extubation: an observational study.

Intensive care medicine·2026
Same author

Outcomes, prognostic factors, and the role of intracranial pressure monitoring in severe community-acquired bacterial meningitis: a multicenter retrospective cohort study.

The Lancet regional health. Europe·2026
Same author

Characterization and outcomes of severe complications after autologous hematopoietic stem-cell transplantation: a retrospective multicenter study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Dyspnea as a marker of prognosis in immunocompromised patients with acute respiratory failure.

Annals of intensive care·2026
Same author

Creation of a dedicated post-intensive care geriatric unit (PIGU), proof of concept and preliminary results.

European geriatric medicine·2026
Same author

Clinical spectrum, outcome and impact of nephrectomy in critically-ill adult patients with emphysematous pyelonephritis: the PYELEMPHY observational retrospective multicenter Study.

Annals of intensive care·2026

Related Experiment Video

Updated: Jan 11, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

8.5K

Obstructive pyelonephritis in intensive care units: A retrospective multicenter study.

Paul Gabarre1, Guillaume Dumas2, Matthieu Raymond3

  • 1Intensive Care Unit, Centre Hospitalier Universitaire Tenon Saint-Antoine, Assistance Publique-Hôpitaux de Paris, 75012 Paris, France; Sorbonne Université, Université Pierre-et-Marie Curie, 75000 Paris, France; Soins Intensifs Néphrologiques et Rein Aigu, Centre Hospitalier Universitaire Tenon, Assistance Publique-Hôpitaux de Paris, 75020 Paris, France.

Journal of Critical Care
|November 13, 2025
PubMed
Summary

Obstructive pyelonephritis is a severe condition with high mortality, often requiring intensive care. Prompt urinary drainage is crucial, particularly for patients in septic shock, to improve outcomes.

Keywords:
Intensive care medicineObstructive pyelonephritisPrognosisSepsisSource control

More Related Videos

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
10:38

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies

Published on: January 16, 2019

20.7K
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.7K

Related Experiment Videos

Last Updated: Jan 11, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

8.5K
Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
10:38

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies

Published on: January 16, 2019

20.7K
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.7K

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Infectious Diseases

Background:

  • Obstructive pyelonephritis presents a significant threat, frequently leading to organ failure and substantial in-hospital mortality.
  • Patients admitted to the intensive care unit (ICU) for this condition often require extensive organ support therapies.

Purpose of the Study:

  • To evaluate the in-hospital mortality rates associated with obstructive pyelonephritis.
  • To identify prognostic factors influencing mortality in ICU patients with obstructive pyelonephritis.

Main Methods:

  • A retrospective, multicenter study included 483 patients admitted to ICUs over a 10-year period.
  • In-hospital mortality was the primary outcome measure.
  • Multivariate analysis was employed to identify factors associated with mortality.

Main Results:

  • Common causes of obstruction included kidney stones, cancer, and ureteral stent issues. Escherichia coli was the predominant pathogen.
  • Factors significantly associated with mortality were vasopressor use, mechanical ventilation, elevated lactate levels, tumor-related obstruction, and stent obstruction.
  • Delayed urinary drainage (>12 hours) increased mortality risk, especially in patients requiring vasopressors.

Conclusions:

  • Obstructive pyelonephritis is a critical illness associated with high in-hospital mortality and organ failure.
  • Timely urinary drainage is essential for improving patient outcomes.
  • Urgent intervention is particularly vital for patients experiencing septic shock.