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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
[Cutaneous squamous cell carcinoma]
1Service de dermatologie, hôpital Cochin-AP-HP. Centre-Université Paris Cité, 123, boulevard de Port-Royal, 75014 Paris, France.
Abstract:
Cutaneous squamous cell carcinoma (CSC), formerly known as squamous cell carcinoma, is the most common skin cancer after basal cell carcinoma, accounting for 20% of all skin cancers. It is a malignant epithelial tumor of keratinocytic origin. Its incidence has risen sharply in recent decades. CEC is characterized by a more rapid evolution than basal cell carcinoma, with a risk of local recurrence and distant lymphatic and hematogenous metastatic dissemination. Early surgical management usually leads to a cure; adjuvant radiotherapy should be considered in cases of poor prognosis. Finally, immunotherapy has supplanted conventional chemotherapy in the management of advanced forms of the disease, thanks to its superior efficacy (40-50% response rate) and much better tolerability.
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