A novel dynamic abdominal wall traction system for open abdomen: preclinical evaluation

This study evaluates the efficacy and safety of Dynatract®, a novel device designed to facilitate early primary closure and prevent aponeurotic retraction in patients with an open abdomen (OA).

A preclinical trial was conducted using a porcine model, comparing two groups: one treated solely with AbThera™ Negative Pressure Wound Therapy (NPWT), and another combining AbThera™ NPWT with Dynatract®. The primary endpoint was to evaluate the distance between fascial edges, with secondary measures including the force required to achieve abdominal closure and overall closure success.

"The Dynatract® group showed a progressive reduction in fascial edge distance over time compared to the control group, with statistically significant differences observed at the caudal and midpoint positions (but not at the cranial position), as well as in the force required to achieve closure after 36 h. Complete fascial closure was achieved in all animals in both groups.