Association between modified Rankin Scale scores and fall risk in post-stroke rehabilitation inpatients: a

Songhui Wu1, Qingfang Zhang1, Jie Yan1

  • 1Department of Rehabilitation, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong province, China.

Scientific Reports
|November 13, 2025
PubMed

Insights

Falls are a common stroke complication. The study found an inverted U-shaped relationship between modified Rankin Scale (mRS) scores and fall risk, peaking at mRS 3, highlighting a key group for fall prevention.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Gerontology

Background:

  • Falls are a frequent complication post-stroke, impeding functional recovery.
  • The modified Rankin Scale (mRS) is standard for stroke assessment, but its link to fall risk is unclear.

Purpose of the Study:

  • To investigate the association between modified Rankin Scale (mRS) scores and the risk of falls in stroke survivors.
  • To identify specific mRS score ranges associated with elevated fall risk for targeted interventions.

Main Methods:

  • A multicenter, cross-sectional study involving 6,192 stroke patients.
  • Data collected via interviews on sociodemographics, clinical factors, falls, and mRS scores.
  • Statistical analyses included univariate, logistic regression, and threshold effect models.

Main Results:

  • 8.46% of patients reported falls.
  • A non-linear, inverted U-shaped association was observed between mRS scores and fall risk, with the highest risk at mRS 3.
  • Fall risk increased by 34% for each mRS point increase below 3, and decreased by 26% for each point increase above 3.

Conclusions:

  • The modified Rankin Scale (mRS) demonstrates an inverted U-shaped relationship with fall risk in stroke patients, peaking at mRS 3.
  • Stroke survivors with an mRS score of 3 represent a critical group for focused fall prevention strategies.
  • Understanding this nuanced relationship can optimize post-stroke care and rehabilitation efforts.