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Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Mesalamine-Induced Eosinophilic Pneumonia
Monish Sharma1, Joseph E Sotelo2, Steve Schultz3
1Radiology, Texas College of Osteopathic Medicine, Fort Worth, USA.
Abstract:
Eosinophilic pneumonia encompasses a group of lung disorders characterized by peripheral blood eosinophilia. While its etiology is often idiopathic or infectious, non-infectious causes, including drug-induced reactions, should also be considered. Common culprits of drug-induced eosinophilic pneumonia include daptomycin, phenytoin, and nitrofurantoin. Mesalamine-induced eosinophilic pneumonia is rare, with only a few cases documented in the literature. We present the case of a 27-year-old male patient who developed unilateral eosinophilic pneumonia following three months of mesalamine therapy for ulcerative colitis. Subsequent discontinuation of mesalamine led to rapid resolution of his symptoms, supporting a diagnosis of mesalamine-induced eosinophilic pneumonia.
Insights
Mesalamine can cause eosinophilic pneumonia, a rare lung disorder. This case highlights mesalamine as a potential cause, with symptoms resolving after drug discontinuation.
Area of Science:
- Pulmonology
- Pharmacology
- Gastroenterology
Background:
- Eosinophilic pneumonia is a lung disorder defined by peripheral blood eosinophilia.
- Causes include idiopathic, infectious, and non-infectious triggers like medications.
- Common drug culprits are daptomycin, phenytoin, and nitrofurantoin.
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