CMV Reactivations During and After Letermovir Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation: A Single-Center Experience

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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
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Edoardo Olivari1,2, Chiara Pavoni2, Alessandra Algarotti2

  • 1University of Milan, Italy.

Mediterranean Journal of Hematology and Infectious Diseases
|November 14, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Allogeneic hematopoietic stem cell transplantationCMVLetermovir prophylaxis

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

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