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Related Concept Videos

Vaccinations01:51

Vaccinations

51.2K
Overview
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Development of Immunocompetence01:22

Development of Immunocompetence

778
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Cancer Vaccines01:30

Cancer Vaccines

939
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Active versus Passive Immunity01:31

Active versus Passive Immunity

9.9K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
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Related Experiment Video

Updated: Jan 11, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
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Research progress in vaccination during pregnancy.

Jiao Zhang1,2, Zhimin Li1, Shiran Li1

  • 1Department of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Frontiers in Immunology
|November 14, 2025
PubMed
Summary

Vaccination during pregnancy is a key strategy to protect mothers and infants from infectious diseases. This review examines vaccine effectiveness, safety, and global recommendations for expectant mothers.

Keywords:
maternal immunizationpregnancyvaccinationvaccine efficacyvaccine safety

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Area of Science:

  • Immunology
  • Maternal-Fetal Medicine
  • Public Health

Background:

  • Pregnant women and infants face heightened susceptibility to infectious diseases.
  • Maternal antibodies transferred via the placenta offer crucial protection to newborns.
  • Vaccination during pregnancy is a vital public health intervention.

Purpose of the Study:

  • To review the effectiveness and safety of vaccines for pregnant women.
  • To summarize global vaccination recommendations for this demographic.
  • To highlight the importance of pregnancy vaccination strategies.

Main Methods:

  • Comprehensive literature review of existing studies on pregnancy vaccination.
  • Analysis of vaccine efficacy and safety data for various infectious diseases.
  • Comparative review of international vaccination guidelines for pregnant individuals.

Main Results:

  • Pregnancy vaccination significantly reduces disease incidence and mortality in mothers and infants.
  • Maternal antibodies provide passive immunity to newborns, enhancing their protection.
  • Diverse global strategies exist, with varying vaccine recommendations.

Conclusions:

  • Vaccination during pregnancy is a safe and effective method for disease prevention.
  • Standardizing and promoting pregnancy vaccination is crucial for global maternal and child health.
  • Continued research and updated recommendations are essential.