[The single centre experience - from Recklinghausen to the present].

Area of Science:

• Endocrinology
• Mineral and Bone Metabolism

Background:

• Parathyroid glands (PG) and associated diseases have been studied since the 19th century.
• Significant evolution in understanding calcium-phosphorus metabolism, diagnostics, and treatments for mineral disorders.
• Historical research laid the foundation for current advancements.

Purpose of the Study:

• To provide a historical review of mineral and bone pathology related to parathyroid glands.
• To highlight the evolution of diagnostic and treatment approaches.
• To showcase modern achievements in endocrinology using a single center as an example.

Main Methods:

• Historical literature review.
• Analysis of anatomical, physiological, morphological, molecular, and genetic aspects of PG.
• Incorporation of innovative laboratory and instrumental methods.

Main Results:

• Demonstrated significant changes in the basic principles of calcium-phosphorus metabolism.
• Showcased advancements in diagnostic methods and treatment options for mineral disorders.
• Highlighted the impact of interdisciplinary knowledge and innovative technologies.

Conclusions:

• Recent advances in PG research enable personalized patient care.
• The historical progression of PG study is crucial for understanding current endocrinology.
• Continued innovation promises further breakthroughs in mineral and bone pathology.