Proteomic Findings in ADHD: A Systematic Review.
Ozan Botan Karabulut1, Dilek Unal1
1Hacettepe Univ. Faculty of Medicine, Department of Child and Adolescent Psychiatry, Ankara, Turkey.
Summary
Proteomics research in attention-deficit hyperactivity disorder (ADHD) shows promise for identifying diagnostic biomarkers. Studies highlight proteins involved in inflammation, neurotransmission, and metabolism, offering potential for early detection and treatment monitoring.
Area of Science:
- Neuroscience
- Biochemistry
- Genetics
Background:
- Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder with significant societal and personal impact.
- Early identification and treatment are vital to mitigate long-term consequences of ADHD.
- Current diagnostic methods lack reliable biomarkers despite advances in neuroimaging, neurophysiology, and genetics.
Conclusions:
- Proteomics holds significant potential for developing reliable biomarkers for ADHD diagnosis and treatment monitoring.
- Further research is needed to translate findings from animal models to human clinical applications.
- Understanding the proteomic landscape of ADHD can inform clinical practice and therapeutic strategies.
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