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Unveiling Infantile Hemangiomas: A Comprehensive Study of Patterns, Presentations, and Complications
Prashansa Jaiswal1, Jyoti Singh1, Aishwarya Dua2
1Department of Dermatology, All India Institute of Medical Sciences, Bhopal, India.
Insights
Infantile hemangiomas are common infant vascular tumors. This study found a female predominance and common head/neck locations, with potential complications like amblyopia.
Area of Science:
- Pediatric Oncology
- Dermatology
- Vascular Biology
Background:
- Infantile hemangioma (IH) is the most common infant vascular tumor, affecting 4-10% of newborns.
- IH presents diverse clinical features, including solitary, multifocal, or segmental lesions, with distinct growth phases.
- Risk factors include prematurity, low birth weight, female sex, and family history.
Purpose of the Study:
- To analyze the clinical characteristics of infantile hemangioma patients.
- Focus on age at onset, presentation, location, size, type, and associated complications.
- To understand the diverse manifestations and risk factors in a tertiary care setting.
Main Methods:
- Retrospective analysis of medical records for infants diagnosed with infantile hemangioma.
- Collected data on demographics, lesion characteristics, and complications for statistical analysis.
- Reviewed 694 hemangiomas in 500 patients.
Main Results:
- 50% of infants had a precursor lesion at birth; 72% were female and delivered at term.
- Strawberry mass morphology (74%) was most common, predominantly in the head and neck (42%).
- 88% showed progressive growth; complications included amblyopia (10 patients with periocular IH), PHACES syndrome, and others.
Conclusions:
- Infantile hemangioma exhibits diverse clinical presentations and potential anomalies.
- Understanding risk factors and early identification of complications is crucial.
- This study provides insights into IH management in a tertiary care setting.
Background:
Infantile hemangioma is the most common vascular tumor in infants, affecting 4% to 10% of this population. It typically appears as a solitary cutaneous hemangioma but can also be multifocal or segmental. The condition progresses through rapid growth, a plateau phase, and gradual involution. Key risk factors include low birth weight, prematurity, female sex, multiple gestations, and family history. Clinical presentation varies among individuals.
Objective:
This study aimed to analyze the clinical characteristics of patients with infantile hemangioma at our hospital, focusing on age at onset, presentation, location, size, type, and complications.
Methods:
A retrospective analysis of medical records of infants diagnosed with infantile hemangioma was conducted. Data were collected for statistical analysis on demographics, lesion characteristics, and complications.
Results:
The study reviewed 694 hemangiomas in 500 patients, with 50% having a precursor lesion at birth. A significant female predominance (72%) was noted, with most patients (72%) delivered at term. The strawberry mass was the most common morphology (74%), primarily located in the head and neck (42%). Of the hemangiomas, 45% were superficial, and 88% showed progressive growth. Ten patients with periocular hemangiomas experienced amblyopia, while other complications included PHACES syndrome, ipsilateral breast hypertrophy, and arteriovenous malformations.
Conclusion:
This study highlights the diverse manifestations, anomalies, and risk factors associated with infantile hemangioma in a tertiary care setting.
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