Treatment Failure in Scabies: Assessment of Risk Factors in a Multicenter Cross-Sectional Study.

Area of Science:

• Dermatology
• Infectious Diseases
• Public Health

Background:

• Scabies treatment failure is a growing global concern.
• Understanding factors influencing treatment outcomes is crucial for effective management.

Purpose of the Study:

• To identify factors associated with treatment failure in scabies patients.

Main Methods:

• A prospective, multicenter observational study involving 230 scabies patients.
• Patients completed questionnaires on adherence and treatment application.
• Outcomes were assessed one month post-treatment initiation.

Main Results:

• Treatment failure occurred in 25.2% of patients.
• Key risk factors for failure included incomplete body application (OR: 14.33), not reapplying after handwashing (OR: 3.5), and not reading information forms (OR: 13.7).
• No demographic or medication factors were linked to treatment failure.

Conclusions:

• Scabies treatment failure is prevalent, primarily linked to improper topical treatment application and hygiene practices.
• Providing clear, written instructions may improve patient adherence and treatment success.