Related Experiment Video
Updated: Jan 6, 2026

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
Published on: September 15, 2023
Multisource Coherence Analysis of the First European Multicenter Cohort Study for Cancer Prevention in People
Antonio Blasco-Calafat1, Vicent Blanes-Selva1, Tobias Fragner2
1Biomedical Data Science Laboratory, Institute of Information and Communication Technologies, Universitat Politècnica de València, Valencia, Spain.
Data coherence varied significantly across European countries in a study of homeless individuals, necessitating country-specific analyses for health research and policy. This highlights the heterogeneity within this population.
Area of Science:
- Public Health
- Health Services Research
- Data Science
Background:
- Ensuring data coherence across multicenter datasets is crucial for reliable health data reuse and to prevent biases.
- Heterogeneity in data can lead to suboptimal generalization of research findings.
- The study addresses data quality for a novel European multicenter dataset on cancer prevention and early detection among the homeless population.
Purpose of the Study:
- To characterize and label data coherence across sites in a European multicenter dataset for homeless individuals.
- To enable research addressing health disparities and healthcare access barriers faced by people experiencing homelessness.
- To adapt and implement a health navigator model within this population.
Main Methods:
- Analysis of a dataset comprising 652 cases from Austria, Greece, Spain, and the United Kingdom.
- Longitudinal data collection via questionnaires at baseline, 4 weeks, and end of intervention.
- Assessment of data variability using information theory and geometric methods to analyze distribution and completeness.
Main Results:
- Substantial variability observed across the 4 pilot countries in overall analysis and specific domains.
- Greatest discrepancies noted in health care empowerment, quality of life, and interpersonal communication.
- Spain showed the most pronounced differences, with high missing values in interpersonal communication and healthcare service use.
Conclusions:
- Health data may be comparable, but significant differences in other questionnaire domains necessitate country-specific analyses.
- The study highlights the heterogeneity among people experiencing homelessness.
- Emphasizes the critical need for data quality assessments to guide future research and policy in this area.
Related Concept Videos
Cancer Survival Analysis
Bias in Epidemiological Studies
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer Prevention
Some...
Confounding in Epidemiological Studies
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...

