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Three-Dimensional Shape Modeling and Analysis of Brain Structures
Published on: November 14, 2019
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Digital tools for analyzing nondiffeomorphic shapes
Henry Kirveslahti1,2,3, Xiaohan Wang1,4
1Department of Mathematics and Computer Science, Laboratory for Topology and Neurosciences, Ecole polytechnique fédérale de Lausanne, Lausanne CH-1015, Switzerland.
Summary
We developed a precise digital algorithm for the Euler Characteristic Transform (ECT), enabling exact shape analysis without information loss. This new method enhances shape inversion and alignment for complex datasets.
Area of Science:
- Computational geometry
- Shape analysis
- Digital topology
Background:
- The Euler Characteristic Transform (ECT) is a landmark-free method for analyzing nondiffeomorphic shapes.
- Current discrete approximations of ECT lead to information loss and inversion challenges.
Purpose of the Study:
- To present a fully digital algorithm for exact ECT computation.
- To introduce the Ectoplasm package for implementing the algorithm.
- To demonstrate the algorithm's utility in real-world shape analysis tasks.
Main Methods:
- Developed a novel, fully digital algorithm for exact Euler Characteristic Transform computation.
- Implemented the algorithm in the Ectoplasm software package.
- Applied gradient descent and adaptive grid search for shape alignment using the exact ECT.
Main Results:
- The algorithm computes ECT exactly, up to computer precision.
- The Ectoplasm package offers a fast and convenient tool for computing distances on real-life datasets.
- Enabled shape inversion, subshape selection, and shape alignment previously not possible with discretized ECT.
Conclusions:
- The exact digital ECT algorithm overcomes limitations of previous approximations.
- The Ectoplasm package facilitates advanced shape analysis, including alignment.
- This work opens new possibilities for statistical shape analysis and related problems.

