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Reducing the Nonindicated Use of IV Hydralazine in the Inpatient Setting
Ashwin Kumar1, John Lynch1, Jennifer Baldwin1
1Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Implementing a redesigned order set significantly reduced nonindicated intravenous hydralazine use in hospitalized patients from 69% to 25%. This intervention, combining decision support with education, enhances medication safety for elevated blood pressure management.
Area of Science:
- Clinical Pharmacy
- Health Informatics
- Patient Safety
Background:
- Elevated blood pressure (BP) is prevalent in hospitalized patients, with intravenous (IV) antihypertensives often misused for non-emergent situations.
- Inappropriate IV antihypertensive use can lead to adverse events like hypotension and acute kidney injury, without improving patient outcomes.
- A significant proportion (69%) of IV hydralazine use at UConn John Dempsey Hospital lacked appropriate indications.
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