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Updated: Jan 11, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Phenolamides: metabolic architects of plant adaptation
Peng Cao1, Shuangqian Shen2, Jun Yang3
1National Key Laboratory for Tropical Crop Breeding, School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, Hainan 572025, China; National Key Laboratory for Tropical Crop Breeding, College of Tropical Agriculture and Forestry, Hainan University, Sanya, Hainan 572025, China.
Abstract:
Phenolamides are specialized plant metabolites with important roles in plant disease resistance and stress tolerance. They serve as biomarkers and effectors of oxidative stress. Moreover, they enhance plant metabolic diversity and potential for acclimation to stress. In this opinion article we focus on recent progress in phenolamide research, including phenolamide biosynthesis, decoration, and transport mechanisms, and we highlight the important role of technological advances in the discovery of new phenolamides and the identification of their biosynthetic genes. We also discuss phytohormone-regulated phenolamide biosynthesis networks and their multifunctional roles in environmental adaptation. We posit that a deeper mechanistic understanding of phenolamide biology will be essential for leveraging these molecules to develop high-value phytoprotectants and advance sustainable agriculture.
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