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Published on: June 29, 2013
Role of Transcerebellar Diameter in Estimating Gestational Age in the Third Trimester: A Comparative Analysis in
Ilayda Gercik Arzik1, Hakan Golbasi1, Sevim Tuncer Can2
1Department of Perinatology, Izmir City Hospital, Izmir, Turkey.
Objectives:
To evaluate the accuracy of transcerebellar diameter (TCD) in estimating gestational age (GA) during the third trimester and compare its predictive value with traditional biometric parameters in appropriate-for-gestational-age (AGA), large-for-gestational-age (LGA), and small-for-gestational-age (SGA) fetuses.
Methods:
In this prospective cross-sectional study, 229 singleton pregnancies between 28 and 40 weeks were categorized into AGA, LGA, and SGA groups based on estimated fetal weight (EFW) and/or abdominal circumference (AC) percentiles. Standardized ultrasonography was used to obtain biometric measurements, including TCD. Correlation coefficients, accuracy within ±7, ±14, and ± 21-day margins, and simple linear regression analyses were calculated for each group.
Results:
TCD showed a strong correlation with GA in all groups (AGA: r = 0.904; LGA: r = 0.920; SGA: r = 0.848). These findings indicate large effect sizes and strong associations between TCD and gestational age across all fetal growth groups. Within ±14 days, TCD accuracy was high across groups (AGA: 88.7%, LGA: 85.0%, SGA: 86.3%; p = .788). Regression models demonstrated high predictive performance in AGA (R2 = 0.838) and LGA (R2 = 0.891) groups, and moderate performance in SGA (R2 = 0.645). TCD outperformed other parameters in LGA and SGA within wider error margins.
Conclusion:
TCD is a reliable, growth-pattern-independent parameter for GA estimation in the third trimester and a valuable alternative when conventional measurements are less reliable.
