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Related Experiment Video

Updated: Jan 11, 2026

Experimental Approaches to Tissue Engineering
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Tissue engineering with bionanomaterials: A new frontier.

Ankit Kumar Dubey1, Hemavathi Brijesh2, Yong Zhang3

  • 1Department of Pharmacy and Institutes for Systems Genetics, Center for High Altitude Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu-610041, Sichuan, China; West China Tianfu Hospital, Sichuan University, Chengdu-610218, Sichuan, China; Department of Biotechnology, School of Applied Sciences, REVA University, Bengaluru-560064, India; iGlobal Research and Publishing Foundation, New Delhi-110059, India; Institute of Scholars, Bengaluru -577102, Karnataka, India.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
|November 15, 2025
PubMed
Summary

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This summary is machine-generated.

Bionanomaterials (BNMs) enhance tissue engineering by mimicking natural structures for regenerative medicine. Further research is needed to overcome challenges in biocompatibility and production for clinical use.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Nanotechnology

Background:

  • Bionanomaterials (BNMs) are crucial in tissue engineering (TE), mimicking natural extracellular matrices (ECMs) due to their nanoscale properties.
  • Their biocompatibility and tunable nature make them ideal for phytomedicine-inspired regenerative therapies.

Purpose of the Study:

  • To review the role of BNMs in tissue engineering.
  • To highlight their synergy with natural therapeutic strategies and potential for unmet clinical needs.

Main Methods:

  • Comprehensive analysis of BNM design, bioactivity, and applications.
  • Focus on natural material sources relevant to phytomedicine.

Main Results:

  • BNMs show efficacy in regenerating bone, cartilage, skin, and neural/vascular tissues.
Keywords:
BNMsFunctionalityNanotechnologyRegenerationTissue engineering

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  • Advantages include enhanced support, targeted bioactivity, and reduced immunogenicity.
  • Challenges include long-term biocompatibility, scalability, and regulatory hurdles.

    • Conclusions:

    • BNMs offer a transformative approach to tissue engineering, integrating phytomedicine for precise regenerative therapies.
    • They enable personalized treatments by incorporating bioactive compounds and mimicking ECMs.
    • Addressing biocompatibility and standardizing production are key for clinical adoption.