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Updated: Jan 11, 2026

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Piloting the novel Evidence Synthesis Equity Companion (ESEC) tool.

Maria Benkhalti1, Talia Salzman1, Prinon Rahman1

  • 1Public Health Agency of Canada, 785 Carling Ave, Ottawa, ON K1S 5H4, Canada.

Annals of Epidemiology
|November 15, 2025
PubMed
Summary

A new tool, the Evidence Synthesis Equity Companion (ESEC), offers step-by-step guidance for incorporating equity into evidence syntheses. This structured approach enhances methods and uncovers crucial evidence for underserved populations.

Keywords:
Evidence synthesisHealth equityLiterature reviewMethodsrapid reviewsystematic review

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Area of Science:

  • Public Health
  • Epidemiology
  • Community Medicine

Background:

  • Growing recognition of the need for evidence on equity-denied populations.
  • Existing frameworks lack step-wise guidance for integrating equity into evidence syntheses.
  • A gap exists in tools that facilitate the documentation of equity considerations.

Purpose of the Study:

  • To adapt an existing tool for health technology assessment into a comprehensive guide for evidence synthesis.
  • To provide step-wise methodological guidance for incorporating equity considerations.
  • To facilitate transparent documentation of equity in evidence synthesis.

Main Methods:

  • Adapted the Equity Checklist for Health Technology Assessment (ECHTA).
  • Complemented guidance with a comprehensive literature search and expert input.
  • Piloted the Evidence Synthesis Equity Companion (ESEC) tool in a rapid review on substance-related mortality.

Main Results:

  • The ESEC tool offers structured guidance for equity considerations at each stage of evidence synthesis.
  • The pilot demonstrated enhanced approaches for equity-focused review questions.
  • The tool enables transparent documentation of the evidence synthesis process and its limitations.

Conclusions:

  • The ESEC tool effectively supports the incorporation of equity throughout the evidence synthesis process.
  • The pilot highlighted benefits for methodology, uncovered evidence, and team collaboration.
  • Further application of ESEC across diverse evidence syntheses is needed to fully understand its value.