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Quality of Life in Breast and Gynecological Cancer: A Review of Systematic Reviews, 1985-2025
Fatma Qurrotunnada1, Erna Rochmawati2
1School of Nursing, Master Program, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia.
Purpose:
Breast and gynecological cancers can significantly impact patients' quality of life (QoL), which has become an important outcome measure in cancer care. This review aims to provide an updated synthesis of the literature on the QoL among patients with breast and gynecological cancers.
Methods:
A review of systematic reviews was conducted using PubMed, Scopus, Science Direct, and Wiley Online Library to identify papers from 1985 to 2025. Publications were screened following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and methodological quality was assessed using the A Measurement Tool to Assess Systematic Review (AMSTAR) criteria. The findings were summarized in tables.
Results:
Twenty-four studies were selected for inclusion. Findings were summarized under the following themes: quality-of-life measurements; treatments (including exercise, therapy, and digital intervention); and QoL among different nations, races, and regions. The EORTC QLQ-C30 emerged as the most widely used assessment tool in cancer research. Most reviews focused on the impact of treatments. According to the reviews, aerobic exercise, Baduanjin exercise, and acupuncture were the top recommended interventions for improving QoL in patients with breast cancer (BC).
Conclusion:
There are many perceived challenges to collecting the data. Most of them involve obstacles in reporting and a variety of designs, interventions, and outcomes, making it hard to identify the most effective methods for improving QoL. However, some interventions have been proven to be effective for BC patients, including aerobic and Baduanjin exercises, yoga, acupuncture, and cognitive-behavioral stress management. Randomized controlled trials are needed to validate and refine treatment protocols. Future systematic reviews and meta-analyses should follow the reporting guidelines.
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