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Intrastriatal Injection of Autologous Blood or Clostridial Collagenase as Murine Models of Intracerebral Hemorrhage
Published on: July 3, 2014
Improvement of neurological function, immune function and inflammatory response in patients with severe cerebral
Bei Yuan1, Qiannan Qi2, Xulei Li2
1Department of General Internal Medicine Ward 2, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Abstract:
After the occurrence of cerebral hemorrhage (CH), patients generally develop neurological disorders and dysphagia, requiring enteral nutrition support. In this study, the research team explored the impact of predictive management-assisted probiotic low-fat nutritional supplements on CH patients. A total of 114 CH patients admitted to our hospital from August 2022 to June 2024 were selected as the study subjects. They were divided into a control group (n=57) using low-fat nutritional supplements and an experimental group (n=57) using probiotic combined with low-fat nutritional supplements. After treatment, the NIHSS of the experimental group was found to be lower than that of the control group, while the ADL was higher than that of the control group (p<0.05). In addition, glutamate (Glu), aspartic acid (Asp), CD8+ and inflammatory factors were lower in the experimental group than in the control group after treatment, whereas glycine (Gly), gamma-aminobutyric acid (GABA), cluster of differentiation (CD)3+, CD4+, CD4+/CD8+ were higher than in the control group (P< 0.05). In conclusion, probiotic low-fat nutrition combined with predictive management significantly improves neurological function.
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