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Related Concept Videos

Diffusion01:21

Diffusion

6.2K
Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
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Diffusion01:12

Diffusion

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Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
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Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

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Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
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Reynolds Transport Theorem01:24

Reynolds Transport Theorem

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The Reynolds transport theorem provides a framework to relate the time rate of change of an extensive property within a system to that in a control volume, which is crucial for analyzing fluid dynamics. Extensive properties, such as mass, velocity, acceleration, temperature, and momentum, can be expressed in terms of the mass of a fluid portion. These properties are called extensive because they depend on the system's size, while intensive properties are their corresponding values per unit...
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Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion03:48

Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion

31.1K
Although gaseous molecules travel at tremendous speeds (hundreds of meters per second), they collide with other gaseous molecules and travel in many different directions before reaching the desired target. At room temperature, a gaseous molecule will experience billions of collisions per second. The mean free path is the average distance a molecule travels between collisions. The mean free path increases with decreasing pressure; in general, the mean free path for a gaseous molecule will be...
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Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models00:57

Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models

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Physiological pharmacokinetic models, often called flow-limited or perfusion models, typically assume a swift drug distribution between tissue and venous blood, creating a rapid drug equilibrium. This premise is based on the idea that drug diffusion is extremely fast, and the cell membrane presents no barrier to drug permeation. In this scenario, where no drug binding occurs, the drug concentration in the tissue equals that of the venous blood leaving the tissue. This greatly simplifies the...
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The Diffusion of Passive Tracers in Laminar Shear Flow
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Diffusion for Diffusion: A versatile multiphysics fields refinement framework in pollutants transportation.

Yinpeng Wang1, Yuancheng Zhan2

  • 1National University of Singapore, Singapore.

Water Research
|November 16, 2025
PubMed
Summary

A new diffusion-model deep learning framework accurately reconstructs pollutant transport fields from limited data. This approach enhances environmental risk assessment and industrial pollution mitigation by improving prediction accuracy and efficiency.

Keywords:
Diffusion modelsMultiphysics field refinementPollutant transportSparse data augmentation

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Area of Science:

  • Environmental Science
  • Computational Fluid Dynamics
  • Machine Learning

Background:

  • Accurate pollutant transport modeling is crucial for environmental risk assessment and industrial pollution control.
  • Current numerical solvers and machine learning methods face challenges in computational efficiency, generalizability, and prediction accuracy.

Purpose of the Study:

  • To develop a novel deep learning framework for refining coupled multiphysics fields in pollutant transport using sparse measurements.
  • To address the limitations of existing methods in terms of efficiency, generalizability, and accuracy.

Main Methods:

  • A physics-informed, equation-constrained deep learning framework based on conditional diffusion models.
  • Application to pollutant diffusion driven by coupled concentration and temperature gradients in 2D transient and 3D steady-state scenarios.
  • Validation using benchmark datasets from finite element simulations and double-color siren imaging.

Main Results:

  • The proposed diffusion-model framework accurately recovers high-dimensional spatiotemporal pollutant fields from limited observations.
  • Consistent outperformance of state-of-the-art baselines (ResNet, Transformer, Fourier Neural Operator) in super-resolution accuracy and robustness.
  • Demonstrated effectiveness across varied source distributions and boundary conditions.

Conclusions:

  • The developed diffusion-model deep learning approach offers a significant advancement in pollutant transport field reconstruction.
  • This method provides a promising pathway for real-time monitoring and analysis in environmental and industrial pollution contexts.
  • The framework shows potential for improving environmental risk assessment and pollution mitigation strategies.