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Related Experiment Video

Updated: Jan 11, 2026

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Transcranial Direct Current Stimulation for Naming Disorders in Poststroke Aphasia: A Meta-analysis of Randomized

Huimin Wang1, Yanan Wang2, Jiawang Dong1

  • 1Department of Rehabilitation, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei.

Archives of Physical Medicine and Rehabilitation
|November 16, 2025
PubMed
Summary

Transcranial direct current stimulation (tDCS) shows promise in improving naming abilities for poststroke aphasia patients, especially those with chronic stroke. Further research is needed due to study limitations.

Keywords:
AphasiaMeta-analysisNaming disorderRehabilitationStrokeTranscranial direct current stimulation

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Area of Science:

  • Neuroscience
  • Neurology
  • Rehabilitation Medicine

Background:

  • Aphasia, a language disorder, frequently occurs after stroke.
  • Naming difficulties are a common and debilitating symptom of poststroke aphasia.
  • Effective treatments for poststroke naming impairments remain an area of active research.

Purpose of the Study:

  • To conduct a meta-analysis evaluating the efficacy of transcranial direct current stimulation (tDCS) for treating naming disorders in poststroke aphasia patients.
  • To synthesize evidence from randomized controlled trials (RCTs) to determine the impact of tDCS on naming abilities.

Main Methods:

  • Systematic review and meta-analysis of RCTs sourced from Web of Science, Cochrane Library, EMBASE, and PubMed up to July 22, 2024.
  • Inclusion criteria focused on RCTs assessing tDCS effects on naming in poststroke aphasia.
  • Data extraction and risk of bias assessment were performed independently by two reviewers, with discrepancies resolved by a third researcher.

Main Results:

  • Twelve studies with 400 participants were included in the meta-analysis.
  • tDCS significantly improved naming abilities in poststroke aphasia patients (SMD=0.25, P=.01).
  • Anodal tDCS showed a significant positive effect on naming function recovery (SMD=0.25, P=.02), particularly in chronic stroke cases (SMD=0.48, P=.01).

Conclusions:

  • Anodal transcranial direct current stimulation (tDCS) offers a potential benefit for improving naming abilities in patients with poststroke aphasia, notably in chronic stages.
  • The findings suggest tDCS as a viable therapeutic option, but methodological limitations in current studies necessitate further rigorous RCTs.
  • Future research should focus on refining tDCS protocols and study designs to confirm its therapeutic value.