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Updated: Jan 11, 2026

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage
Published on: November 4, 2010
Usefulness of AirSeal Leak Test for taTME-Assisted Surgery for Lower Rectal Cancer
Yume Minagawa1, Yasumitsu Hirano1, Sohei Akuta1
1Department of Gastroenterological Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
Introduction:
Anastomotic leakage is a major complication after low anterior resection for rectal cancer, particularly in transanal total mesorectal excision (taTME) cases, where the low anastomotic level makes conventional leak testing difficult. We developed a novel leak test using the AirSeal system to improve intraoperative detection of leakage in such cases.
Materials And Surgical Technique:
This technique was applied in patients undergoing low anterior resection combined with taTME for lower rectal cancer within 10 cm of the anal verge, reconstructed using the single-stapling technique. After anastomosis, the AirSeal system was set to a flow rate of 20 L/min and a pressure of 8 mmHg, while laparoscopic intra-abdominal pressure was maintained at 10-12 mmHg. The pelvic cavity was filled with saline, and the anastomosis was inspected for air or water column leakage.
Discussion:
The AirSeal-assisted leak test may be helpful for reliable intraoperative identification of anastomotic leakage by utilizing a controlled pressure differential. It may facilitate the prevention of leakage and stenosis, warranting further prospective validation.

