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Total Joint Arthroplasty in Solid Organ Transplant Patients
Farouk Khury1, Garrett Ruff2, Anzar Sarfraz2
1Department of Orthopedic Surgery, NYU Langone Health, NYU Langone Orthopedic Hospital, 301 East 17 Street, New York, NY 10003, USA; Division of Orthopedic Surgery, Rambam Health Care Campus, The Ruth and Bruce Rappaport Faculty of Medicine, Haifa 3109601, Israel.
The Orthopedic Clinics of North America
|November 16, 2025
Summary
Solid organ transplantation (SOT) recipients often require total joint arthroplasties (TJAs) due to degenerative joint disease. Careful management is key to improving outcomes for these complex patients.
Area of Science:
- Orthopedic Surgery
- Transplant Medicine
- Immunology
Background:
- Increased survival rates in solid organ transplantation (SOT) lead to a higher incidence of degenerative joint diseases.
- Solid organ transplant recipients present unique challenges for joint replacement surgery, including immunosuppression and infection risks.
Purpose of the Study:
- To review the challenges and management strategies for total joint arthroplasties (TJAs) in solid organ transplant recipients.
- To highlight the importance of optimizing outcomes and quality of life for SOT patients undergoing TJAs.
Main Methods:
- Literature review focusing on perioperative management of SOT patients undergoing TJAs.
- Analysis of complication rates and functional outcomes in this specific patient population.
Main Results:
- Total joint arthroplasties (TJAs) in SOT patients can provide significant pain relief and functional improvement despite higher complication risks.
- Meticulous preoperative evaluation, tailored antibiotic prophylaxis, and appropriate implant selection are critical for successful outcomes.
Conclusions:
- Multidisciplinary collaboration is essential for managing SOT patients undergoing TJAs.
- Optimizing perioperative care can reduce complications and enhance the quality of life for SOT recipients requiring joint replacement.
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