Breaking plant family barriers: Sensor-helper NLR pairs enable cross-kingdom immune defense
Manman Zhang1, Cheng Li1, Fengquan Liu1
1Department of Plant Pathology, College of Agriculture, Guizhou University, Guiyang, 550025, China.
Journal of Integrative Plant Biology
|November 17, 2025
Abstract:
This commentary on Du et al. (2025) demonstrates that transferring paired sensor-helper NLRs from Solanaceae to non-asterid species (rice, soybean, and Arabidopsis) overcomes restricted taxonomic functionality, enabling resistance to bacterial leaf streak without fitness costs, and unlocking cross-kingdom immune potential for crop protection.
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