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Population Pharmacokinetics Model and Simulation of Unbound and Total Valproic Acid in Epileptic Children Using a

Tingting Yue1, Limei Zhao2, Ya'nan Chen3

  • 1Department of Neurosurgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Basic & Clinical Pharmacology & Toxicology
|November 17, 2025
PubMed
Abstract

Keywords:
epileptic childrenpopulation pharmacokineticsprotein bindingtherapeutic drug monitoringvalproic acid

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