Related Experiment Video
Updated: Jan 11, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Association Between Wake-Time Movement Behaviors and Weight Loss Maintenance
Chelsea L Kracht1, Denver M Y Brown2, Anna M Gorczyca1
1Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
Objective:
We examined whether wake-time movement composition was associated with weight loss maintenance among individuals who experienced clinically meaningful weight loss (> 5% of initial weight) using compositional data analysis.
Methods:
This was a secondary analysis from a behavioral weight loss maintenance intervention on weight regain over 12 months following clinically meaningful 3-month weight loss. Body weight was assessed at baseline, after weight loss (3 months), and at end of intervention (15 months). Wake-time behaviors (sedentary time [ST], light physical activity [LPA], and moderate-to-vigorous PA [MVPA]) were assessed at two time points during the maintenance intervention using accelerometry. Compositional data analysis was used to examine associations between wake-time movement composition and weight regain (kg).
Results:
Among 153 individuals (80.4% female, 69.9% White), wake-time movement composition was related to weight regain (p = 0.001). MVPA was negatively associated with weight regain (p's < 0.05). Reallocating 10 min/day from ST or LPA to MVPA was associated with less weight regain (ST: -0.32 kg [-0.53, -0.12]; LPA: -0.37 kg [-0.59, -0.15]). Individuals who maintained clinically meaningful weight loss and those who did not differed in wake-time movement composition, driven by MVPA (36.1 vs. 24.3 min/day).
Conclusions:
The composition of wake-time behaviors, specifically MVPA, reduces weight regain after clinically meaningful weight loss in a behavioral weight loss maintenance intervention.
Trial Registration:
ClinicalTrials.gov identifier: NCT01664715.
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