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Updated: Jan 11, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
S1 guideline for imaging diagnostics for skin diseases
Maximilian Deußing1,2, Sandra Schuh3, Janis Thamm3
1Department of Dermatology and Allergy, LMU Munich, Munich, Germany.
This guideline reviews non-invasive skin imaging techniques like dermoscopy and optical coherence tomography (OCT). It details their applications in diagnosing skin conditions and highlights the potential of AI to enhance diagnostic accuracy.
Area of Science:
- Dermatology
- Medical Imaging
- Artificial Intelligence
Background:
- Non-invasive skin imaging is crucial for in vivo examination, with established methods like dermoscopy and sonography widely used.
- Emerging techniques including optical coherence tomography (OCT), reflectance confocal microscopy (RCM), and line-field confocal OCT (LC-OCT) are increasingly adopted in clinical practice.
- Advanced methods like multiphoton tomography and optoacoustic imaging show significant promise for future applications.
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