Treatment of pediatric abdominal pain: what is the evidence?

Miguel Saps1, Samantha Arrizabalo1

  • 1Division of Pediatrics Gastroenterology, Hepatology and Nutrition, Miller School of Medicine, University of Miami, Miami, FL, USA.

Insights

New guidelines offer evidence-based treatments for pediatric abdominal pain disorders (APDs), including irritable bowel syndrome (IBS) and functional abdominal pain (FAP). Hypnotherapy and CBT are strongly recommended for improved quality of life.

Area of Science:

  • Pediatric Gastroenterology
  • Evidence-Based Medicine
  • Clinical Practice Guidelines

Background:

  • Abdominal pain disorders (APDs), such as irritable bowel syndrome (IBS) and functional abdominal pain (FAP), are common in children and impair quality of life.
  • Management of pediatric APDs has historically lacked standardized, evidence-based approaches.

Purpose of the Study:

  • To summarize the first evidence-based treatment guidelines for pediatric IBS and FAP.
  • To provide practical guidance for clinicians managing these conditions.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) from 1984 to June 2023.
  • Searches conducted in PubMed, Embase, and Cochrane CENTRAL databases.
  • Updated literature search for studies published after June 2023.

Main Results:

  • Strong recommendations for hypnotherapy and cognitive behavioral therapy (CBT).
  • Conditional recommendations for probiotics, symbiotics, peppermint oil, soluble fiber, and certain medications.
  • Guidelines are supported by a systematic review of RCTs.

Conclusions:

  • These guidelines standardize pediatric APD management based on evidence.
  • They offer practical tools for clinicians in a complex treatment landscape.
  • Future work should address knowledge gaps and assess guideline impact on outcomes.
Abstract

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