Related Experiment Video
Updated: Jan 11, 2026

Author Spotlight: Exploring the Potential of Massage Therapy in Cerebral Palsy Using Animal Models
Published on: August 11, 2023
Treatment of pediatric abdominal pain: what is the evidence?
Miguel Saps1, Samantha Arrizabalo1
1Division of Pediatrics Gastroenterology, Hepatology and Nutrition, Miller School of Medicine, University of Miami, Miami, FL, USA.
Insights
New guidelines offer evidence-based treatments for pediatric abdominal pain disorders (APDs), including irritable bowel syndrome (IBS) and functional abdominal pain (FAP). Hypnotherapy and CBT are strongly recommended for improved quality of life.
Area of Science:
- Pediatric Gastroenterology
- Evidence-Based Medicine
- Clinical Practice Guidelines
Background:
- Abdominal pain disorders (APDs), such as irritable bowel syndrome (IBS) and functional abdominal pain (FAP), are common in children and impair quality of life.
- Management of pediatric APDs has historically lacked standardized, evidence-based approaches.
Purpose of the Study:
- To summarize the first evidence-based treatment guidelines for pediatric IBS and FAP.
- To provide practical guidance for clinicians managing these conditions.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) from 1984 to June 2023.
- Searches conducted in PubMed, Embase, and Cochrane CENTRAL databases.
- Updated literature search for studies published after June 2023.
Main Results:
- Strong recommendations for hypnotherapy and cognitive behavioral therapy (CBT).
- Conditional recommendations for probiotics, symbiotics, peppermint oil, soluble fiber, and certain medications.
- Guidelines are supported by a systematic review of RCTs.
Conclusions:
- These guidelines standardize pediatric APD management based on evidence.
- They offer practical tools for clinicians in a complex treatment landscape.
- Future work should address knowledge gaps and assess guideline impact on outcomes.
Introduction:
Abdominal pain disorders (APDs), including irritable bowel syndrome (IBS) and functional abdominal pain - not otherwise specified (FAP), are highly prevalent in children and significantly impact quality of life. This review highlights advances addressing the need for standardized, evidence-based management in this population.
Areas Covered:
This review summarizes the first evidence-based treatment guidelines for pediatric IBS and FAP, developed jointly by the European and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. The recommendations were based on a systematic review of randomized controlled trials identified through searches in PubMed, Embase, and Cochrane CENTRAL databases [1984 - June 2023]. Strong recommendations were issued for hypnotherapy and cognitive behavioral therapy, with conditional suggestions for probiotics, symbiotics, peppermint oil, soluble fiber, and selected pharmacologic agents. To complement this work, we performed an updated literature search covering studies published after June 2023.
Expert Opinion:
These guidelines represent a critical advancement in standardizing the management of pediatric APDs by showing how each recommendation is supported by the available evidence. They offer practical guidance for clinicians navigating a complex and often fragmented treatment landscape. Future efforts should prioritize addressing current knowledge gaps and evaluating the impact of these recommendations on clinical outcomes.
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis II: Collaborative Care
Assessment:
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.

