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Improving Translational Accuracy

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

Improving Translational Accuracy

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

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Related Experiment Video

Updated: Jun 29, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

Correction: Optimizing C-TIRADS for sub-centimeter thyroid nodules using machine learning-derived feature importance.

Dongming Guo¹, Zhihui Lin¹, Jiajia Wang¹

¹Department of Interventional Ultrasound, Cancer Hospital of Shantou University Medical College, Shantou, China.

Frontiers in Endocrinology

|November 17, 2025

Summary

This study corrects a previously published article's DOI. The correction ensures proper citation and access to the research findings.

Area of Science:

Endocrinology
Metabolism

Keywords:

C-TIRADS SHAP machine learning microcarcinoma risk stratification sub-centimeter thyroid nodules ultrasound

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