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Updated: May 3, 2026
Chronic Salmonella Infected Mouse Model
Published on: May 31, 2010
Recurrent meningitis due to Salmonella arizonae in an adult with AIDS: case presentation and next-generation
Jairo Lizarazo1, Catering Rodriguez2, Efrain Montilla-Escudero2
1Hospital Universitario Erasmo Meoz, Cúcuta, Colombia.
Background:
Invasive non-typhoidal Salmonella disease is a leading cause of morbidity and mortality worldwide, primarily affecting children, the elderly, and immunocompromised adults, particularly those living with HIV. Salmonella meningitis is rare, except in sub-Saharan Africa. Salmonella arizonae is associated with reptiles and exceptionally causes meningitis in humans.
Case Summary:
We present the case of an adult man living with HIV who presented five episodes of bacterial meningitis due to S. arizonae within a period of 8 months. The patient improved after performing cholecystectomy and with optimization of antiretroviral treatment and prolonged antibiotic therapy. Genomic study confirmed that S. arizonae is sensitive to antibiotics.
Conclusion:
This case illustrates a rare form of S. arizonae meningitis. The identity of the etiological agent was confirmed by next-generation sequencing analysis.
Insights
Salmonella arizonae meningitis is rare but can occur in immunocompromised individuals. This case highlights successful treatment with cholecystectomy, optimized antiretroviral therapy, and antibiotics.
Area of Science:
- Infectious Diseases
- Microbiology
- Neurology
Background:
- Invasive non-typhoidal Salmonella disease causes significant global morbidity and mortality.
- Salmonella meningitis is uncommon, particularly outside sub-Saharan Africa.
- Salmonella arizonae, linked to reptiles, rarely causes human meningitis.
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