Related Experiment Video
Updated: Jan 11, 2026
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Invasive laser acupuncture vs. electroacupuncture for non-specific chronic low back pain: protocol for a randomized
Yejin Hong1, Dongwoo Nam1,2, Changsop Yang3
1Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital, Seoul, Republic of Korea.
Background:
This study aims to evaluate the short-term efficacy of 650 nm invasive laser acupuncture (ILA) compared to conventional electroacupuncture (EA) in reducing pain in patients with non-specific chronic low back pain (NSCLBP).
Method:
This is a prospective, multicenter, randomized, single-blind, controlled trial. Ninety patients with NSCLBP will be recruited and randomly assigned (1:1) to receive either 650 nm ILA or EA. Treatments will be administered at the bilateral acupoints BL23, BL24, BL25, and GB30 for 10 min per session, twice weekly for 4 weeks (8 sessions in total). The primary outcome is the change in the Visual Analog Scale (VAS) score 1 week after treatment completion. Secondary outcomes include VAS scores at interim and follow-up time points, Oswestry Disability Index, European Quality of Life Five Dimension Five-Level Scale, and the proportion of responders. Safety assessments and adverse event monitoring will be conducted throughout the trial.
Conclusion:
This multicenter randomized controlled trial compares the effects of ILA and EA with the change in VAS as a primary efficacy endpoint in 90 patients with NSCLBP. This findings will provide clinical evidence of the comparative efficacy and safety of 650 nm ILA versus EA in patients with NSCLBP, supporting its potential as a viable non-pharmacological treatment option.
Clinical Trial Registration:
https://cris.nih.go.kr/cris/search/detailSearch.do?search_lang=E&focus=reset_12&search_page=M&pageSize=10&page=undefined&seq=29960&status=5&seq_group=29960, identifier KCT0010475.
