Related Experiment Video
Updated: Jan 11, 2026
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Association between abnormalities on chest computed tomography and pulmonary function in patients with respiratory
Luciano Folador1,2, Vicente Bohrer Brentano1, Ravena Maya Cardoso da Silva2
1Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Objective:
To assess the prevalence and type of residual lung abnormalities on chest computed tomography (CT) and pulmonary function testing (PFT) variables in patients with respiratory symptoms related to post-COVID-19 condition at 12 months of follow-up, and to analyze associations between CT findings and PFT parameters.
Materials And Methods:
The CT findings were evaluated by two radiologists, who calculated semiquantitative CT scores. The PFTs included spirometry, plethysmography, and the diffusing capacity of the lung for carbon monoxide.
Results:
Thirty-seven patients were included in the study. On CT scans of the chest acquired at 12 months of follow-up, 78.3% of the patients exhibited residual abnormalities, including reticular opacities, in 75.7%; traction bronchiectasis/bronchiolectasis, in 43.2%; and fibrosis-like findings, in 43.2%. The mean overall CT score was 9.30 ± 2.59. Patients with fibrosis-like findings had significantly lower total lung capacity (68.6% vs. 80.6% of the predicted value; p = 0.018). A moderate negative correlation was found between the overall CT score and total lung capacity (rs = -0.49; p = 0.003).
Conclusion:
It seems that a significant proportion of patients with respiratory symptoms related to post-COVID-19 condition demonstrate residual lung abnormalities on chest CT at 12 months of follow-up, with a substantial prevalence of fibrosis-like findings. Such abnormalities are associated with restrictive lung disease.
More Related Videos
Related Concept Videos
01:30Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
01:27Pneumothorax-II
Clinical Manifestations:
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:31Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...