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A Haemophilus influenzae-associated mycotic aneurysm months after treated bacteremia
Josiah Bennett1, Sarah Lohsen2, Elizabeth Y Kim2
1Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Background:
Invasive nontypeable Haemophilus influenzae (NTHi) infections increased dramatically in the Atlanta area in 2017-2018. Most isolates from these infections belonged to two closely related genetic lineages and were likely being spread through sexual networks of men living with HIV.
Case Summary:
We present a case of a 63-year-old male with well-controlled HIV and treated NTHi pericarditis and bacteremia who we diagnosed with an infected right superficial femoral artery pseudoaneurysm due to NTHi. The causative strain belonged to one of the lineages identified in the 2017-2018 case clusters.
Conclusion:
This case illustrates that novel disease phenotypes continue to emerge for unusually pathogenic strains of NTHi.
Insights
Invasive nontypeable Haemophilus influenzae (NTHi) infections, particularly in men with HIV, are increasing. A recent case highlights NTHi causing a rare pseudoaneurysm, indicating evolving disease presentations.
Area of Science:
- Infectious Diseases
- Bacteriology
- HIV Medicine
Background:
- Invasive nontypeable Haemophilus influenzae (NTHi) infections saw a significant rise in Atlanta during 2017-2018.
- The majority of NTHi isolates were from two related genetic lineages, suggesting transmission within networks of men living with HIV.
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