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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

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Related Experiment Video

Updated: Jun 14, 2026

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
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Invasive fusariosis after CD19 chimeric antigen receptor T-cell therapy.

Rita Wilson Dib1, Annoir Shayya2, Emily A Siegrist1

  • 1Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

ASM Case Reports
|November 17, 2025
PubMed
Summary

Invasive fusariosis is a rare complication after chimeric antigen receptor T-cell (CAR-T) therapy. This case highlights the importance of suspecting Fusarium infections in CAR-T recipients presenting with concerning symptoms.

Area of Science:

  • Oncology
  • Infectious Diseases
  • Immunology

Background:

  • Invasive fusariosis is an uncommon opportunistic infection.
  • Chimeric antigen receptor T-cell (CAR-T) therapy is a growing treatment for hematologic malignancies.
Keywords:
CAR-TFusariumcase reportskin nodules

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  • Post-CAR-T invasive fusariosis is rarely documented.