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Updated: Jan 11, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Indication-based electronic prescribing intervention reduces unnecessary meropenem use in a safety-net hospital: a
Jannet Manuela Reyna-Quito1,2, Robert Glowacki1, Huiyuan Zhang3
1Division of Infectious Diseases, Cook County Health, Chicago, IL, USA.
Abstract:
This quasi-experimental before-and-after intervention study evaluated an indication-based electronic prescribing alert in a 450-bed tertiary care hospital. Implementation reduced meropenem use by 41% without compromising patient safety, demonstrating the effectiveness of this targeted antimicrobial stewardship strategy.
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