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Updated: Jan 11, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Assessment of Physical Activity Domains During Pregnancy and Their Association With Perinatal Outcomes in Women With
R L A Oliveira1,2, L Primo de Carvalho Alves1,2,3, Y Ferrão1,2
1Universidade Federal das Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil (RLAO, LPCA, YF, VGO, BFA).
Abstract:
Background: Pregnant women with psychiatric disorders are vulnerable to mental health decline and obstetric complications. Although physical activity (PA) benefits pregnancy, little is known about how its domains-household, occupational, transport, leisure-manifest in this group and relate to outcomes. This study examined PA patterns across domains and their associations with psychiatric symptom severity and obstetric outcomes. Methods: This cross-sectional subanalysis included 64 pregnant women with psychiatric diagnoses at a public maternity hospital in Brazil. PA was measured using the Pregnancy Physical Activity Questionnaire, diagnosis via SCID-5-CV, and symptom severity with the Clinical Global Impression. Obstetric outcomes came from medical records. Only moderate-to-vigorous PA was analyzed. Results: Most participants (84.6%) met WHO recommendations for weekly PA, mainly through household activities (median: 315 min/week). Leisure, transport, and occupational domains showed minimal activity (median: 0 min/week). Higher household PA was linked to adverse obstetric outcomes (P = 0.009). Leisure-time PA was associated with gestational diabetes (P = 0.003). No significant correlations appeared with psychiatric severity. Conclusion: While overall PA volume met health recommendations, it was predominantly in the domestic sphere. These patterns reflect structural and gender-based vulnerabilities and underscore the importance of context and autonomy in evaluating the health impacts of physical activity during pregnancy in this population.

