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A Septicemic Child due to a Novel Streptococcal Species, Streptococcus gwangjuensis
Benjawan Comhangpol1, Sawita Srisawat2, Naowarat Wangnadee1
1Roi Et Hospital, Roi Et, Thailand.
Insights
A rare case of septicemia caused by Streptococcus gwangjuensis in a child with acute myeloid leukemia was successfully treated. This finding highlights the importance of identifying novel pathogens in immunocompromised patients.
Area of Science:
- Infectious Diseases
- Hematology
- Microbiology
Background:
- Septicemia poses a significant threat to immunocompromised individuals, particularly those with hematological malignancies.
- Acute myeloid leukemia (AML) increases susceptibility to severe infections due to neutropenia.
- Streptococcus gwangjuensis is a rare pathogen, with limited data on its clinical significance, especially in pediatric cases.
Abstract:
We report a case of septicemia due to Streptococcus gwangjuensis in an immunocompromised 8-year-old child. The final diagnosis was febrile neutropenia associated with acute myeloid leukemia and septicemia. The patient was successfully treated with chemotherapy, granulocyte colony-stimulating factor, leukodepleted packed red cell transfusions, piperacillin/tazobactam, and meropenem. S. gwangjuensis was identified using sodA and gyrB amplicon-based next-generation sequencing. The isolate was susceptible to all β-lactam antibiotics.
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