Related Experiment Video
Updated: Jan 11, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Upper Gastrointestinal Bleeding Secondary to Gastric Invasion by Diffuse Large B-cell Lymphoma
Helen Paglia1, Marco Noriega2, Kinnari R Kher3
1Internal Medicine, Memorial Healthcare, Savannah, USA.
None:
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma subtype. We present a case of an 80-year-old male with upper gastrointestinal bleeding (UGIB), ultimately diagnosed with DLBCL involving the liver, gallbladder, inferior vena cava, and stomach, leading to a large gastric ulcer. Despite initial suspicion of alcohol-related UGIB, imaging revealed multiple masses with extranodal lymphoma involvement. Endoscopic hemostasis was attempted but was complicated by tumor-induced neovascularization. This case highlights a rare cause of UGIB and underscores the challenges in diagnosis and management of malignancy-induced bleeding.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Other Disorders of Digestive System
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...