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Updated: Jun 23, 2026
05:37
Intravitreous Injection for Establishing Ocular Diseases Model
Published on: October 1, 2007
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Intravitreal injection delivered volume under different environmental and training conditions
Mateus Lins Dos Santos1, Lucas Andrade Santos1, Alexandre Lima Cardoso1
1Hospital de Olhos de Sergipe, R. Campo do Brito, 995, São José, Aracaju, SE, 49020-380, Brazil.
Summary
Intravitreal injection (IVI) accuracy varies significantly with syringe type, operator skill, and background color. Optimizing these factors is crucial for precise medication delivery in ophthalmology.
Area of Science:
- Ophthalmology
- Medical Device Engineering
- Pharmacology
Background:
- Accurate medication delivery is critical in ophthalmology, particularly for intravitreal injections (IVI).
- Environmental factors and operator variability can potentially impact the precision of IVI volumes.
Purpose of the Study:
- To assess the accuracy of intravitreal injection volumes.
- To investigate the influence of varying environmental conditions and operator training levels on IVI accuracy.
Main Methods:
- Evaluated three syringe models and 30G needles using distilled water.
- Tested injections against different background colors (beige, black, blue, green, white).
- Assessed impact of operator proficiency (student, resident, surgeon) and training on volume accuracy.
Main Results:
- Significant differences in volume accuracy were observed across syringe types (p < 0.001).
- Operator proficiency (p = 0.007) and training status (p < 0.001) significantly affected volume accuracy.
- Background color, specifically green and beige versus black, showed significant differences (p = 0.007, p = 0.008).
Conclusions:
- Intravitreal injection volumes are significantly influenced by syringe selection, operator expertise, and visual background.
- These variables necessitate careful consideration to ensure precision and efficacy in ophthalmic treatments.
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