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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Patient Experience With Rechargeable Deep Brain Stimulation Generators for Obsessive-Compulsive Disorder.

Tommy Liu1, Mohammed Hasen2, Danika L Paulo1

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Rechargeable deep brain stimulation (DBS) systems require frequent charging for obsessive-compulsive disorder (OCD) patients, averaging 1-2 days between charges. While beneficial, managing these routines is crucial for effective OCD treatment.

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Deep brain stimulationEquipment designImplantable neurostimulatorsObsessive-compulsive disorder

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Biomedical Engineering

Background:

  • Rechargeable deep brain stimulation (DBS) systems offer extended device lifespan and reduced surgical replacement frequency.
  • Obsessive-compulsive disorder (OCD) patients require higher stimulation settings, leading to more frequent recharging needs for these systems.

Purpose of the Study:

  • To evaluate patient experiences with rechargeable implantable pulse generators (RC IPGs) for OCD treatment.
  • To analyze charging routines, perceived vs. actual charge burden, and unique considerations of RC technology in psychiatric DBS therapy.

Main Methods:

  • Interviews with OCD patients implanted with RC IPGs to assess recharging experiences.
  • Gathering battery usage data directly from device downloads.
  • Utilizing surveys and device data to compare self-reported vs. actual charging metrics and calculate weekly charge burden.

Main Results:

  • OCD patients experienced significantly shorter recharge intervals (average 29.5 hours) compared to movement disorder patients.
  • Despite daily integration, the weekly charge burden averaged 209.5 minutes, with discrepancies between perceived and actual charging times.
  • Some patients reported anxiety or fixation related to battery levels, highlighting psychological impacts.

Conclusions:

  • RC IPGs enhance DBS therapy for OCD by reducing surgical risks and costs associated with frequent replacements.
  • OCD patients require recharging every 1-2 days, a substantial increase compared to the 1-2 week intervals typical for movement disorder patients.
  • Personalized DBS therapy must consider individual patient needs, and primary cell systems may be more suitable for patients struggling with charging management.