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Related Concept Videos

Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

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Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
270
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

301
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
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Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

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The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
290
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
415
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

302
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
302
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

242
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Syphilis complicated with pericardial effusion: a case report.

Jingtao Ma1, Zhiying Zhang1, Meng Chen1

  • 1Zhejiang Chinese Medical University, Jiaxing, 314001, China.

BMC Infectious Diseases
|November 18, 2025
PubMed
Summary

Syphilis infection, though rare, can cause pericardial effusion. This case highlights the importance of syphilis testing in unexplained effusions, as penicillin treatment resolved symptoms and effusion.

Keywords:
Cardiovascular syphilisLatent syphilisPericardial effusionSyphilis

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Syphilology

Background:

  • Pericardial effusion is common, often caused by inflammation or infection.
  • Syphilis is an extremely rare cause of pericardial effusion.

Purpose of the Study:

  • To report a rare case of latent syphilis presenting as pericardial effusion.
  • To emphasize the importance of considering syphilis in unexplained pericardial effusions.

Main Methods:

  • A case presentation of a 76-year-old male with unexplained pericardial effusion.
  • Diagnostic workup included pericardial fluid analysis and syphilis serology.
  • Treatment with penicillin was administered.

Main Results:

  • The patient presented with symptoms of dizziness and dyspnea, with imaging confirming pericardial effusion.
  • Syphilis serology was strongly positive in both serum and pericardial fluid.
  • Penicillin treatment led to complete resolution of symptoms and effusion.

Conclusions:

  • Syphilis should be considered in the differential diagnosis of unexplained or recurrent pericardial effusions.
  • Testing for syphilis is recommended after excluding more common etiologies.
  • This case underscores the diverse presentations of syphilis.