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Updated: Jan 11, 2026

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
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Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Yuqiang Qian1,2, Fengjiao Hui3, Wenchao Niu2

  • 1Laboratory of Organ Regeneration and Transplantation of The Ministry of Education, China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, The First Hospital of Jilin University, Changchun, China.

Genome Biology
|November 18, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
CBEsDddAEditing efficiencyEditing windowGenome editing

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