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Updated: Jan 11, 2026

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Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
Published on: August 1, 2018
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Identification of gut microbes related molecular subtypes and prognostic markers in breast cancer
1Department of Breast Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Computer Methods in Biomechanics and Biomedical Engineering
|November 18, 2025
Abstract:
Gut microbe-related genes (GMRGs) are crucial in breast cancer prognosis, immune regulation, and therapy response. A 16-GMRG prognostic model accurately predicts survival and immunotherapy efficacy. Two heterogeneous subtypes with distinct immune landscapes were identified. Drug sensitivity and Mendelian randomization analyses further validated their clinical relevance. These findings offer new insights for personalized breast cancer treatment.

