Clinical Implementation of RHD NIPT in a Tertiary Obstetric Centre in Western Australia

A clinically robust RHD non-invasive prenatal test (RHD NIPT) was developed to predict fetal RhD status and optimise RhD Ig use for RhD-negative pregnant women in Western Australia. Using rigorous methodology and stakeholder engagement we created clinical guidelines and educational support tools, such as reference guides and consumer brochures, to enhance test uptake. Six months post-implementation, 90% of healthcare professionals surveyed felt confident offering the test, with 87% having ordered it. A guideline review of 50 women confirmed they all received appropriate RhD Ig use. This successful implementation of RhD NIPT screening in our tertiary obstetric centre ensured safe, targeted care for RhD-negative pregnancies.